宋彦龄

教授
电话：（0592）2187621 （实验室）
传真：（0592）2187601
电子邮箱： ylsong@xmu.edu.cn
实验室：卢嘉锡楼703、704

个人简历：

副教授、特任研究员 （beat365官方网站化学系 2019.11–至今）

特任副研究员/副研究员 （上海交通大学分子医学研究院2018–2019）

助理研究员 （福州大学生物科学与工程学院2016–2018）

理学博士 （beat365官方网站化学系化学生物学专业 2010–2016）

理学学士 （beat365官方网站化学系化学生物学专业 2006–2010）

获得荣誉：

beat365官方网站“南强青年拔尖人才支持计划”（2019）

上海市“晨光计划”A类（2018）

研究兴趣：
分子定向进化、微纳界面组装及识别机制、微流控分析、液体活检、单细胞分析、生物传感

近期主要代表论著：

1. 1. Jialu Zhang, Bingqian Lin, Lingling Wu, Mengjiao Huang, Xingrui Li, Huimin Zhang, Jia Song, Wei Wang, Gang Zhao,* Yanling Song,* and Chaoyong Yang*, DNA Nanolithography Enables Highly Ordered Recognition Interface in Microfluidic Chip for Efficient Capture and Release of Circulating Tumor Cells, Angew. Chem. Int. Ed. 2020, DOI: 10.1002/anie.202005974

2. 2. M.J. Huang, J.J. Yang, T. Wang, J. Song, J.L. Xia, L.L. Wu, W. Wang, Q.Y. Wu, Z. Zhu, Y.L. Song*, C.Y. Yang*, Homogeneous, Low-volume, Efficient and Sensitive Quantitation of Circulating Exosomal PD-L1 for Cancer Diagnosis and Immunotherapy Response Prediction. Angew. Chem. Int. Ed doi.org/10.1002/anie.201916039(2020)

3. 3. L.L. Wu, ^# H.M. Ding, ^# X. Qu, ^# X.A. Shi, J.M.Yang, M.J. Huang, J.L. Zhang, H.M. Zhang, J. Song, L. Zhu, Y.L. Song*, Y.Q. Ma*, C.Y. Yang*, Fluidic Multivalent Membrane Nanointerface Enables Synergetic Enrichment of Circulating Tumor Cells with High Efficiency and Viability, J. Am. Chem. Soc. doi.org/10.1021/jacs.9b13782(2020)

4. 4. J. Song, Y. Zheng, M.J. Huang, L.L. Wu, W. Wang, Z. Zhu, Y.L. Song*, C.Y. Yang, A Sequential Multi-dimensional Analysis Algorithm for Aptamer Identification based on Structure Analysis and Machine Learning. Anal. Chem. doi.org/10.1021/acs.analchem.9b05203(2020)

5. 5. Y.L. Song; Y.Z. Shi; M.J. Huang; W. Wang; Y. Wang; J.Cheng.; Z.C. Lei; Z. Zhu.; C.Y. Yang*, Bioinspired Engineering of a Multivalent Aptamer-Functionalized Nanointerface to Enhance the Capture and Release of Circulating Tumor Cells. Angew. Chem. Int. Ed. 58(8), 2236(2019)

6. 6. M.J. Huang, J. Song, P.F. Huang, X.F. Chen, W. Wang, Z. Zhu, Y.L. Song*, C.Y. Yang*. Molecular Crowding Evolution for Enabling Discovery of Enthalpy-Driven Aptamers for Robust Biomedical Applications. Anal. Chem. 91, 10879(2019)

7. 7. B.Q. Lin ^#, Y. An^#, L.Y. Meng, H.M. Zhang, J. Song, Z. Zhu, W. Liu*, Y.L. Song*, C.Y. Yang*. Control of CRISPR-Cas9 with small molecule-activated allosteric aptamer regulating sgRNAs. Chem. Commun., 55, 12223(2019)

8. 8. Y.L. Song; B.Q. Lin; Tian, T.; X. Xu; W. Wang; Q.Y. Ruan; J.J. Guo; Z. Zhu; C.Y. Yang*, Recent Progress in Microfluidics-Based Biosensing. Analytical Chemistry 91 (1), 388(2019)

9. 9. M.X. Gao; J.J. Guo; Y.L. Song *; Z. Zhu*; C.Y. Yang*. Detection of T4 Polynucleotide Kinase via Allosteric Aptamer Probe Platform, ACS Appl. Mater. Interfaces, 9, 38356(2017)

10. 10. Y.L. Song; Tian, T; Y.Z Shi; W.L. Liu; Y. Zou, T. Khajavand; Z. Zhu; C.Y. Yang*. Enrichment and Single-Cell Analysis of Circulating Tumor Cells, Chemical Science, 8, 1736(2017)

11. 11. Tian, T; Y. An; Y. Wu; Y.L. Song*; Z. Zhu; C.Y. Yang*. Integrated Distance-Based Origami Paper Analytical Device for One-Step Visualized Analysis, ACS Applied Materials Interfaces, 9, 30480(2017)