个人简历:
博士(浙江大学,1998)
硕士(南开大学,1991)
学士(浙江大学,1985)
博士后(台湾清华大学,美国Johns Hopkins University)
研究兴趣:
异相催化:新型多孔有机聚合物材料搭载金属催化剂的设计、合成、表征与应用 有机合成:基于炔丙醇为原料的杂环化合物新合成方法研究; 药物合成:应用新合成方法合成药物和天然化合物; 香料合成:天然香料生产工艺研发。
近期主要代表论著:
2017
40. Conjugated Microporous Polymer as Heterogeneous Ligand for Highly Selective Oxidative Heck Reaction.Yun-Bing Zhou, Yu-Qing Wang, Li-Chao Ning, Zong-Cang Ding, Wen-Long Wang, Cheng-Ke Ding, Ren-Hao Li, Jun-Jia Chen, Xin Lu, Yun-Jie Ding,*, and Zhuang-Ping Zhan*. J. Am. Chem. Soc. 2017, 139, 3966−3969.
39. Thiophene-Alkyne-Based CMPs as Highly Selective Regulators for Oxidative Heck Reaction. Ren-Hao Li, Zong-Cang Ding, Cun-Yao Li, Jun-Jia Chen, Yun-Bing Zhou, Xiao-Ming An, Yun-Jie Ding*, and Zhuang-Ping Zhan*. Org. Lett.2017, 19, 4432−4435.
38. Copper(I)-Catalyzed Synthesis of 4,5-Dihydropyrazolo[1,5-a]pyrimidines via Cascade Transformation of N-Propargylic Sulfonylhydrazones with Sulfonyl Azides. Zong-Cang Ding, Xiao-Ming An, Jia-Hao Zeng, Zhao-Ning Tang, and Zhuang-Ping Zhan*. Adv. Synth. Catal. ,2017,359, 3319-3324.
37. Palladium/Phosphorus-Doped Porous Organic Polymer as Recyclable Chemoselective and Efficient Hydrogenation Catalyst under Ambient Conditions. Zong-Cang Ding, Cun-Yao Li, Jun-Jia Chen, Jia-Hao Zeng, Hai-Tao Tang,Yun-Jie Ding,* and Zhuang-Ping Zhan*. Adv. Synth. Catal. ,2017,359, 2280 – 2287.
36. Synthesis of pyrazolo[5,1-a]isoquinolines through copper-catalyzed regioselective bicyclization of N-propargylic sulfonylhydrazones. Hai-Tao Tang, Jia-Hao Zeng, Jun-Jia Chen, Yun-Bing Zhou, Ren-Hao Li and Zhuang-Ping Zhan *. Org. Chem. Front., 2017, 4, 1513–1516.
2016
35. Silver(I)-Catalyzed Tandem Sigamatropic Rearrangement/1,3‑H Shift/6π Aza-electrocyclization of N‑Propargylic Hydrazones: A Mild Synthetic Route to 1,6-Dihydropyridazines. Zong-Cang Ding, Lu-Chuan Ju, Ying Yang, Xiao-Ming An, Yun-Bing Zhou, Ren-Hao Li, Hai-Tao Tang,Cheng-Ke Ding, and Zhuang-Ping Zhan*.J. Org. Chem., 2016, 81 (9), 3936–39414.
34. Synthesis of 5,6-Dihydropyrazolo[5,1‑a]isoquinolines through Indium(III)-Promoted Halocyclizations of N‑Propargylic Sulfonylhydrazones. Ren-Hao Li, Cheng-Ke Ding, Ya-Nan Jiang, Zong-Cang Ding, Xiao-Ming An, Hai-Tao Tang, Qi-Wei Jing,and Zhuang-Ping Zhan*. Org. Lett. 2016, 18, 1666−1669.
2015
33. Synthesis of 4‑Arylidenepyrazolones by a Gold-Catalyzed Cyclization/Arylidene Group Transfer Cascade of N‑Propioloyl Hydrazones.Zong-Cang Ding, Hai-Tao Tang, Ren-Hao Li, Lu-Chuan Ju, and Zhuang-Ping Zhan*. J. Org. Chem. 2015, 80, 9307−9313.
32. A Polymer-Bound Monodentate-P-Ligated Palladium Complex as a Recyclable Catalyst for the Suzuki–Miyaura Coupling Reaction of Aryl Chlorides.Yun-Bing Zhou, Cun-Yao Li,Min Lin, Yun-Jie Ding* and Zhuang-Ping Zhan*. Adv. Synth. Catal.2015, 357, 2503 –2508.
31.Synthesis of 5,6-Dihydropyrazolo[1,5‑c]quinazolines through Gold-Catalyzed ChemoselectiveBicyclization of N‑Propargylic Sulfonylhydrazones.Hai-Tao Tang, Kai Xiong, Ren-Hao Li, Zong-Cang Ding, and Zhuang-Ping Zhan*, Org. Lett.2015, 17, 326-329.
2014
30. Synthesis of Polysubstituted Pyrazoles by aPlatinum-Catalyzed Sigmatropic Rearrangement/Cyclization Cascade. Jia-Jie Wen,Hai-Tao Tang, Kai Xiong, Zong-Cang Ding, and Zhuang-Ping Zhan*, Org. Lett.2014, 16, 5940−5943.
29. Base-Catalyzed N_N Bond Cleavage of Hydrazones:Synthesis of a-AminoKetones. Hai-Tao Tang, Yun-Bing Zhou, Yu Zhu, Hong-ChaoSun, Min Lin, and Zhuang-Ping Zhan*,Chem. Asian J. 2014, 9, 1278 -1281.
28. Selective synthesis of 4-(sulfonyl)-methyl-1Hpyrazolesand (E)-4,5-dihydro-1H-pyrazoles from N-allenic sulfonylhydrazones. Yu Zhu, Jun-JieHong, Yun-Bin Zhou, Yu-Wei Xiao, Min Lin and Zhuang-Ping Zhan*,Org.Biomol. Chem. 2014, 12, 3797–3801.
27. Silver(I)-catalyzed annulation for the regioselectivesynthesis of N-imino-γ-carbolinium ylides from hydrazones of indole-3-carbonylderivatives and propargylic alcohols. Yu Zhu, Xin-Rui Shen, Hai-Tao Tang, MinLin and Zhuang-Ping Zhan*, Org. Biomol. Chem. 2014, 12, 9514-9518.
2013
26. Lewis Base Catalyzed Synthesis of Multisubstituted4-Sulfonyl-1 H-Pyrazole Involving a Novel 1, 3-Sulfonyl Shift. Yu Zhu, Wen-TingLu, Hong-Cao Sun, Zhuang-Ping Zhan*,Org.Lett. 2013, 15,4146-4149.
25. Copper (I)-Catalyzed Stereoselective Synthesis of(1E,3E)-2-Sulfonyl-1,3-dienes from N-Propargylic Sulfonohydrazones. Yu Zhu, Hai-Tao Tang, Zhuang-Ping Zhan*, Adv. Synth. Catal.2013,355, 1291-1296.
24. One-Pot Synthesis of Pyrazoles through a Four-StepCascade Sequence.Lu Hao, Junjie Hong, Jun Zhu, Zhuang-Ping Zhan*,Chem.Eur. J.2013, 19, 5715-5720.
23.Chemoselective synthesis of substituted pyrazolesthrough AgOTf-catalyzed cascade propargylicsubstitution-cyclization-aromatization. Su-Xia Xu, Lu Hao, Tao Wang,Zong-Cang Ding, Zhuang-Ping Zhan*,Org.Biomol. Chem.2013, 11, 294-298.
2012
22. Synthesis ofAcrylonitriles through an FeCl3-Catalyzed Domino Propargylic Substitution/Aza-Meyer–SchusterRearrangement Sequence. Lu Hao, Feng Wu, Zong-Cang Ding, Su-Xia Xu, Yan-Li Ma,Li Chen, and Zhuang-Ping Zhan*,Chem. Eur. J.2012, 18, 6453–6456.
21.The Synthesis of Aromatic Heterocycles from Propargylic Compounds. Wen Jia-Jie, Yu Zhu, Zhuang-Ping Zhan*, Asian J. Org. Chem., 2012,1, 108-129.(综述)
20. Microwave-assisted synthesis of2-aminopyrimidines from silica gel-adsorbed propargyl alcohols and guanidine,Feng Wu, Zhuang-Ping Zhan*,Heterocycles 2012,85, 1891-1896.
2011
19. Atom-Economical Chemoselective Synthesis of 1,4-Diynesand Polysubstituted Furans/Pyrroles from Propargyl Alcohols and TerminalAlkynes. Tao Wang, Xin-liang Chen, Li Chen, and Zhuang-ping Zhan*,Org. Lett.2011, 13, 3324-3327.
18. Nucleophilic Substitution of SecondaryAlkyl-Substituted Propargyl Acetates: An Economic and Practical IndiumTrichloride Catalyzed Access. Min Lin , Lu Hao, Xiao-tao Liu, Qing-zhen Chen,Feng Wu, Ping Yan, Su-xia Xu, Xin-liang Chen, Jia-jie Wen, Zhuang-ping Zhan*, Synlett2011,665-670.
17. Copper(II)-Catalyzed Synthesis of Pyrimidines fromPropargylic Alcohols and Amidine: A Propargylation–Cyclization–Oxidation TandemReaction. Min Lin, Qing-zhen Chen, Yu Zhu, Xin-liang Chen, Ji-jun Cai,Ying-ming Pan,Zhuang-ping Zhan*,Synlett2011, 1179-1183.
16. The Construction ofFive-Membered Heterocycles by Transition Metal-Catalyzed Cyclization ofPropargylic Compounds.Lu Hao and Zhuang-Ping Zhan*, Current Organic Chemistry2011, 15, 1625-1643(综述)
2010
15. Chemoselective Cascade Synthesis of N-FusedHeterocycles via Silver(I) Triflate-Catalyzed Friedel–Crafts/N-C Bond FormationSequence. Lu Hao, Yingming Pan, Tao Wang, Min Lin, Li Chen, Zhuang-ping Zhan*,Adv. Synth. Catal.,2010, 352, 3215-3222.
14. Solvent-Free Solid Acid-Catalyzed NucleophilicSubstitution of Propargylic Alcohols: A Green Approach for the Synthesis of 1,4-diynes. Tao Wang, Rui-da Ma and Zhuang-ping Zhan*, Green Chem. 2010, 12, 1576–1579.
13. Facile one-pot synthesis of three differentsubstituted thiazoles from propargylic alcohols. Xun Gao, Ying-ming Pan, MinLin, Li Chen and Zhuang-ping Zhan*. Org. Biomol. Chem. 2010, 8, 3259–3266. ( highlightedby Synfacts,Synfacts, 2010, 9, 996)
12. One-pot highly efficient synthesis of substitutedpyrroles and N-bridgehead pyrroles by zinc-catalyzed multicomponent reaction. Xiao-taoLiu, Lu Hao, Min Lin, Li Chen and Zhuang-pingZhan*. Org. Biomol. Chem. 2010, 8, 3064–3072.
2009
11. Brønsted Acid-Catalyzed Propargylation/CycloisomerizationTandem Reaction: One-Pot Synthesis of Substituted Oxazoles from PropargylicAlcohols and Amides. Ying-ming Pan, Fei-jian Zheng, Hai-xin Lin, and Zhuang-ping Zhan*.J. Org. Chem. 2009, 74, 3148-3151.(Impact factor: 4.6)(highlighted by Synfacts, Synfacts, 2009, 7, 724.)
10. A One-Pot Synthesis of Substituted Furans UsingCu(OTf)2-Catalyzed Propargylation/Cycloisomerization Tandem Reaction. Ying-mingPan, Su-yan Zhao, Wen-hua Ji and Zhuang-pingZhan*. J. Comb. Chem. 2009, 11, 103-109.
2008
9. Indium(III) Chloride CatalyzedPropargylation/Amination/Cycloisomerization Tandem Reaction: One-Pot Synthesisof Highly Substituted Pyrroles from Propargylic Alcohols, 1,3-DicarbonylCompounds and Primary Amines. Xiao-tao Liu, Lei Huang, Fei-jian Zheng, and Zhuang-ping Zhan*. Adv. Synth. Catal. 2008,350, 2778-2788. [highlighted by Synfacts,(Synfacts2009, 3, 249)]
8. FeCl3-CatalyzedPropargylation/Cycloisomerization Tandem Reaction: A Facile One-Pot Synthesisof Substituted Furans. Wen-hua Ji, Ying-ming Pan, Su-yan Zhao, Zhuang-ping Zhan*.Synlett. 2008,3046-3052.
2007
7.Copper (II) triflateCatalyzed Nucleophilic Substitution of Propargylic Acetates with Enoxysilanes.A Straightforward Synthetic Routeto Polysubstituted Furans. Zhuang-pingZhan,* Shao-pei Wang, Xu-bin Cai, Hui-juan Liu, Jing-liang Yu and Yuan-yuanCui, Adv. Synth. Catal. 2007, 349, 2097-2102.
6. FeCl3-Catalyzed Nucleophilic Substitution ofPropargylic Acetates with Enoxysilanes.Zhuang-pingZhan,* Xu-bin Cai, Shao-pei Wang, Jing-liang Yu, Hui-juan Liu and Yuan-yuan Cui,J. Org. Chem.2007, 72, 9838-9841.
2006
5. BiCl3-Catalyzed propargylic substitution reactionof propargylic alcohols with C-, O-, S- and N-centered nucleophiles. Zhuang-Ping Zhan,* Wen-zhen Yang,Rui-feng Yang, Jing-liang Yu, Jun-ping Li and Hui-juan Liu, Chem. Commun. 2006, 3352-3354.
4. A General and Efficient FeCl3–CatalyzedNucleophilic Substitution of Propargylic Alcohols.Zhuang-PingZhan,* Jing-liang Yu, Hui-juan Liu,Yuan-yuan Cui, Rui-fengYang, Wen-zhen Yang, and Jun-ping Li, J.Org. Chem.2006, 71,8298-8301.
3. FeCl3-CatalyzedCoupling of Propargylic Acetates with Alcohols. Zhuang-Ping Zhan,* Hui-JuanLiu, Synlett2006, 14, 2278.
2. FeCl3-CatalyzedPropargylation of Aromatic Compounds with Propargylic Acetates. Zhuang-Ping Zhan,*Yuan-Yuan Cui andHui-Juan Liu, Tetrahedron Letters, 2006,47,9143.
1. Bismuth Trichloride–Catalyzed C-Alkylation ofPyrroles with Electron-Deficient Olefins. Zhuang-PingZhan*, Jiang-Liang Yu, Wen-Zhen Yang, Synth. Commun. 2006, 36, 1373.